If the children were being sedated...

[Jean-Pierre]

I am with Cariad on this.  In my view it is better to try to maintain at least a tenuous grip on reality, rather than stray in to the realms of fantasy. 

There are no sedatives that have a two hour delay.  And particuloarly in the case of chidren who metabolise faster anyway. 

To cite personal experience, two of my children used to rush around, and then fall so deeply asleep that an earthquake would not shift them.  So it is not beyond the bounds of possibility that they were simply tired and fell deeply aspleep.   

[John]

I am with Cariad on this.  In my view it is better to try to maintain at least a tenuous grip on reality, rather than stray in to the realms of fantasy. 

There are no sedatives that have a two hour delay.  And particuloarly in the case of chidren who metabolise faster anyway. 

To cite personal experience, two of my children used to rush around, and then fall so deeply asleep that an earthquake would not shift them.  So it is not beyond the bounds of possibility that they were simply tired and fell deeply aspleep.

Kate herself suggests the idea of stranger sedation so given that she was a fully qualified anaesthetist, I wonder how she thought it would have been dispensed?

[Jean-Pierre]

Kate herself suggests the idea of stranger sedation so given that she was a fully qualified anaesthetist, I wonder how she thought it would have been dispensed?

More probably at the time of abduction, rather than some sort of premptive drugging in the late afternoon. 

[icabodcrane]

I am with Cariad on this.  In my view it is better to try to maintain at least a tenuous grip on reality, rather than stray in to the realms of fantasy. 

There are no sedatives that have a two hour delay.  And particuloarly in the case of chidren who metabolise faster anyway. 

 

Well,  it appears Kate, herself,  entered the realms of fantasy you speak of  ;

"Could  Madeleine's apparently excessive tiredness on that last Thursday afternoon have been caused by some kind of tranquillizer administered earlier in the day, or even the night before ?"

(  Kate's book, page 130  )   

[John]

Well,  it appears Kate, herself,  entered the realms of fantasy you speak of  ;

"Could  Madeleine's apparently excessive tiredness on that last Thursday afternoon have been caused by some kind of tranquillizer administered earlier in the day, or even the night before ?"

(  Kate's book, page 130  )

Nice quote Icabodcrane      I hadn't realised Kate was also suspicious that the kids had been doped earlier that day. 

Remember too that the children had dinner while the parents had a beer at the Paraiso Beach Bar that afternoon according to waiter João.


www.abcnews.go.com/print?id=3637499

[stephen25000]

Perhaps you should read this article  Jean Pierre on that subject. There are plenty of others.

Meanwhile I await the answer from Johnson and Johnson, as I indicated before, if you had been taking notice. >@@(*&)

http://www.theguardian.com/politics/2003/feb/09/health.nhs

[icabodcrane]

The children ate at around 6ish and were asleep at around 8ish right? So you have a sedative administered orally that takes two hours to take effect?

Although the children were said to be tired that night, their parents showed no concern at them being left alone so I assume that they weren't abnormally tired or displaying signs of sedation like floppiness for example.

Remember that Kate Mccann was a trained anaesthesiologist so  would be very aware of the signs of sedation.

I assume that you are claiming that the sedative was mixed in with either food or drink, so no slow release capsule could be used?

What sedative would take two hours to have effect yet last many hours afterwards?

Kate thought Madeleine might have been given a tranquillizer the night  before  the evening she disappeared

As you say,  Kate is a qualified anesthetist  ...   so I guess she must be aware of a tranquillizer that can be administered to a child in the evening  ...  where the child wakes up bright as a button at 7.30am the next morning  ...  and then becomes excessively tired some 18 hours after the tranquillizer was given

I wasn't aware such a  'slow acting'  sedative  existed  ...   but Kate is the expert,  and she seems to think it does

[ferryman]

... if you had been taking notice.

Of what?

[stephen25000]

... if you had been taking notice.

Of what?

That's your problem ferryman, not mine.

[Jean-Pierre]

Kate thought Madeleine might have been given a tranquillizer the night  before  the evening she disappeared

As you say,  Kate is a qualified anesthetist  ...   so I guess she must be aware of a tranquillizer that can be administered to a child in the evening  ...  where the child wakes up bright as a button at 7.30am the next morning  ...  and then becomes excessively tired some 18 hours after the tranquillizer was given

I wasn't aware such a  'slow acting'  sedative  existed  ...   but Kate is the expert,  and she seems to think it does

I did pass this in front of my son who dabbles in such things and he was puzzled too.  So who knows.

[Jean-Pierre]

Perhaps you should read this article  Jean Pierre on that subject. There are plenty of others.

Meanwhile I await the answer from Johnson and Johnson, as I indicated before, if you had been taking notice. >@@(*&)

http://www.theguardian.com/politics/2003/feb/09/health.nhs

Of course it goes on - indeed it is the basis of the film the Contant Gardener.  But are you actually suggesting that Calpol Night (given that it received approval in January 2007) comes into that category?  If so then you are so far away with the faries that you are beyond help.   

Maybe you fondly imagine the reply from Johnson and Johnson will be different from that posted further up the thread (if you had been paying attention).  I fear you will be a bit disappointed.   

[icabodcrane]

I did pass this in front of my son who dabbles in such things and he was puzzled too.  So who knows.

It  is  puzzling that Kate  (  a qualified anesthetist  )  would think that a tranquillizer could be taking affect some 18 hours after administration

Especially given that even the effects of deep anaesthetic  (  the type used in surgery  )  have  98%  worn off  after 15 hours

[stephen25000]

Of course it goes on - indeed it is the basis of the film the Contant Gardener.  But are you actually suggesting that Calpol Night (given that it received approval in January 2007) comes into that category?  If so then you are so far away with the faries that you are beyond help.   

Maybe you fondly imagine the reply from Johnson and Johnson will be different from that posted further up the thread (if you had been paying attention).  I fear you will be a bit disappointed.   

I never said such a thing as you know.

Testing drugs before general release is a standard procedure.

Didn't you know that John Pierre ?

Perhaps it is you who is spending too much time at the bottom of the garden with the fairies.

[Jean-Pierre]

It  is  puzzling that Kate  (  a qualified anesthetist  )  would think that a tranquillizer could be taking affect some 18 hours after administration

Especially given that even the effects of deep anaesthetic  (  the type used in surgery  )  have  98%  worn off  after 15 hours

I can only agree, it is a puzzle. 

[ferryman]

One question that intrigues me is whether Amaral's reference to calpol night in his book would be libel by Portuguese law.

It certainly would by UK ...

MADELEINE SLEEPS BADLY

One of the police officers who went to the McCanns' home in England, reported that a medical monitoring chart for Madeleine was posted in the kitchen. This referred to her sleep problems and made clear that she was waking several times in the night. The paternal grandfather stated that Kate gave the little girl - and also the twins - Calpol, a medication designed to facilitate falling asleep. That seems to be a common practice in Great Britain; they even talk about a "Calpol generation." In recent years, the possible presence of an antihistamine with sedative effects in Calpol has aroused great controversy. Recently, the same laboratory put Calpol Night on the market, whose ingredients clearly list that it contains an antihistamine.

Amaral has stopped (just) short of saying Kate and Gerry gave Madeleine the drug.

But that is the impression far too many people have formed, including Morais, who wrote a particularly vicious blog on the subject.

So is Amaral's reference libel?