It depends what you call evidence. In my opinion there's evidence that the McCanns were up to something. There's no evidence that their daughter had noteworthy DNA or that she was abducted to be kept until old enough to breed.
The problem you have with that is that what Amaral wrote in his book detailing what he thought was evidence quite simply was not. It was just his belief.
He based his book, his theories, his contribution as coordinator on Madeleine's case on ephemera which lasted only in his fevered certainty for as long as it was not subject to scrutiny and when it was, simply vanished like a puff of smoke.
There is absolutely no evidence that the McCanns "were up to something". If there had been one or both of them would probably still be doing time in a Portuguese jail and like Joana before her, there would have been no need for anyone to bother keeping the flame alight in the search for Madeleine.
Please bear in mind that tagging a libel with 'opinion' doesn't make it less of a libel.