The Level Of Haloperidol In SC's System at TOD.

[Holly Goodhead]

Dr Vanezis refers to traces found: 

http://miscarriageofjustice.co/index.php?action=dlattach;topic=199.0;attach=698

The lab refers to 15 nanograms per millilitre of blood:

http://miscarriageofjustice.co/index.php?action=dlattach;topic=207.0;attach=750

To my mind this information suggests such small quantities that it was irrelevant to SC's wellbeing.

I might be way off the mark here in terms of relating the drink driving limit to haloperidol but based on the drink driving limits of 80 milligrammes of alcohol per 100 millilitres of blood and converting the labs figures above to the drink driving limits:

0.0015 milligrammes of haloperidol per 100 millilitires of blood = level of haloperidol found in SC's blood.  Hence Dr Vanezis referred to a trace. 

80 milligrammes of alcohol per 100 millilitres of blood = max drink and drive limit

This isn't an aspect of the case I have paid much attention to but where does all this stuff come from re SC being oversedated and suffering from Parkinson like symptons? 

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[Myster]

Glynis Howard measured 15 nanograms of Haloperidol per millilitre of blood. In other words a MEDIUM dose (13.1 to 24 ng/mL) according to the study article. And that was almost month after her last intramuscular injection.

You can't compare alcohol levels to those of Haloperidol, because they have totally different effects!

[Holly Goodhead]

Glynis Howard measured 15 nanograms of Haloperidol per millilitre of blood. In other words a MEDIUM dose (13.1 to 24 ng/mL) according to the study article. And that was almost month after her last intramuscular injection.

You can't compare alcohol levels to those of Haloperidol, because they have totally different effects!

Chemist Alexander Allen also measured 15 nanograms per millilitre of blood. Where are you getting the info from that this equates to a medium dose?

http://miscarriageofjustice.co/index.php?action=dlattach;topic=207.0;attach=748

According to Dr Vanezis' interpretation of what he was told by the lab the amount detected was little more than a trace. 

I was just comparing the minute levels of haloperidol found per 100 millilitre with the alcohol limit for drink driving to test Dr Vanezis' claims of a trace.

It seems to me all that was detected in SC's system was a mere trace.

[Myster]

Chemist Alexander Allen also measured 15 nanograms per millilitre of blood. Where are you getting the info from that this equates to a medium dose?

http://miscarriageofjustice.co/index.php?action=dlattach;topic=207.0;attach=748

According to Dr Vanezis' interpretation of what he was told by the lab the amount detected was little more than a trace. 

I was just comparing the minute levels of haloperidol found per 100 millilitre with the alcohol limit for drink driving to test Dr Vanezis' claims of a trace.

It seems to me all that was detected in SC's system was a mere trace.

From the study article you posted in the other thread.

[Myster]

From the study article you posted in the other thread.

Sorry... it was the one Caroline posted, as you've probably discovered already.

[Holly Goodhead]

Sorry... it was the one Caroline posted, as you've probably discovered already.

Yes it was an article Caroline posted.  I thought it related to Haloperidol and the effects on
plasma levels.  But even if it is describing low, medium, high doses of Haloeridol measured by Nanogram of Haloperidol detected per millilitre of blood, the amount detected in SC's blood only just put her into the medium dose range.  Where does all the info come from re SC being oversedated and suffering Parkinson like symptoms?

Haloperidol detected in SC's blood - 15 nanograms of Haloperidol per millilitre of blood.

Low dose = 2 - 13 nanograms of Haloperidol per 1 millilitre of blood

Med dose = 13.1 - 24 nanograms of Haloperidol per 1 millilitre of blood

High dose = 24.1 - 35 nanograms of Haloperidol per 1 millilitre of blood

[Myster]

Yes it was an article Caroline posted.  I thought it related to Haloperidol and the effects on
plasma levels.  But even if it is describing low, medium, high doses of Haloeridol measured by Nanogram of Haloperidol detected per millilitre of blood, the amount detected in SC's blood only just put her into the medium dose range.  Where does all the info come from re SC being oversedated and suffering Parkinson like symptoms?

Haloperidol detected in SC's blood - 15 nanograms of Haloperidol per millilitre of blood.

Low dose = 2 - 13 nanograms of Haloperidol per 1 millilitre of blood

Med dose = 13.1 - 24 nanograms of Haloperidol per 1 millilitre of blood

High dose = 24.1 - 35 nanograms of Haloperidol per 1 millilitre of blood

Armchair doctors?

I'm off here shortly for most of today... power cut for maintenance. See ya!

[adam]

Haloperidol is a very powerful drug. It has up to 100 side effects. Most of which would stop Sheila from committing the massacre.

Sheila being on Haloperidol means she could not have committed something so violent, physical, intense, lenghty & complicated. However she was easy for Bamber to control.

[Holly Goodhead]

Haloperidol is a very powerful drug. It has up to 100 side effects. Most of which would stop Sheila from committing the massacre.

Sheila being on Haloperidol means she could not have committed something so violent, physical, intense, lenghty & complicated. However she was easy for Bamber to control.

If Haloperidol prevented SC from being responsible and made it easy for JB to manipulate her have you any ideas why the prosecution didn't beat the drum about this at trial?

Please provide a source from a medical expert confirming any side-effects suffered by SC.

[Caroline]

If Haloperidol prevented SC from being responsible and made it easy for JB to manipulate her have you any ideas why the prosecution didn't beat the drum about this at trial?

Please provide a source from a medical expert confirming any side-effects suffered by SC.

Her doctor said that her reported symptoms were in line with being over sedated.

[Holly Goodhead]

Her doctor said that her reported symptoms were in line with being over sedated.

Is there anything from SC's GP in this regard?  He was the last medically qualified person to meet with her. 

On 9th Aug Dr Ferguson referred to the side-effects as "slightly sedating" and "slight muscle stiffening". 

Any idea of the date of her last injection?  She was having fortnightly injections and it was talked about halving the dose by injecting the same amount monthly? 

[APRIL]

Is there anything from SC's GP in this regard?  He was the last medically qualified person to meet with her. 

On 9th Aug Dr Ferguson referred to the side-effects as "slightly sedating" and "slight muscle stiffening". 

Any idea of the date of her last injection?  She was having fortnightly injections and it was talked about halving the dose by injecting the same amount monthly?

My God! If she was said to be over sedated on monthly injections of 100mg, I can't begin to imagine what sort of state she'd have been in when she was getting fortnightly injections of 200mg.

[Holly Goodhead]

Her doctor said that her reported symptoms were in line with being over sedated.

Ok I can now see the WS you have attached above is dated 18th Sept.  Dr Ferguson talks of correspondence from Dr Angeloglou dated 15th July asking for SC's dose to be reduced as she felt she was receiving too high a dose.  He also talks about a description he received about SC's last weeks of life that she was becoming over sedated and yet he doesn't mention this in his WS of 9th Aug.  This makes me think the description was not from SC's GP, Dr Angeloglou, but fed to him by EP based on the views of lay witnesses.     

[APRIL]

Ok I can now see the WS you have attached above is dated 18th Sept.  Dr Ferguson talks of correspondence from Dr Angeloglou dated 15th July asking for SC's dose to be reduced as she felt she was receiving too high a dose.  He also talks about a description he received about SC's last weeks of life that she was becoming over sedated and yet he doesn't mention this in his WS of 9th Aug.  This makes me think the description was not from SC's GP, Dr Angeloglou, but fed to him by EP based on the views of lay witnesses.   

Dr Wilkinson, locum to Dr Angeloglou, saw Sheila once on July 11th?. She injected her with 100mg of Haloperidol -HALF her usual dose- and understood that, according to her records, Sheila had been receiving monthly injections.

[Holly Goodhead]

My God! If she was said to be over sedated on monthly injections of 100mg, I can't begin to imagine what sort of state she'd have been in when she was getting fortnightly injections of 200mg.

The point is the amount detected in SC's blood at time of death was within the low end of the moderate range in terms of dosage 15ng/1ml.

Do you know the date SC received her last injection.  I don't know much about this.  Did she have to attend a clinic or was she able to self-administer?