The Calpol claim revisited.

[Sunny]

Thanks Misty for your link but I don't consider one article to be conclusive evidence that Calpol Night was released as late as September. I am not saying it was released prior to May either or that the McCanns used it on their children.

I have found that it was approved for sale in January 2007 and I have this from March 2007.

Why would Boots have a fact sheet on Calpol Night (last changed in March 2007) if they weren't selling it until the autumn?

https://www.boots.com/wcsstore/cmsassets/Boots/Content/Products/Child%20Cough%20Cold%20-%20CAT:%20A00000558/10069294.P/calpol.pdf

I am not saying my information is conclusive either by the way.

[Mr Gray]

Thanks Misty for your link but I don't consider one article to be conclusive evidence that Calpol Night was released as late as September. I am not saying it was released prior to May either or that the McCanns used it on their children.

I have found that it was approved for sale in January 2007 and I have this from March 2007.

Why would Boots have a fact sheet on Calpol Night (last changed in March 2007) if they weren't selling it until the autumn?

https://www.boots.com/wcsstore/cmsassets/Boots/Content/Products/Child%20Cough%20Cold%20-%20CAT:%20A00000558/10069294.P/calpol.pdf

I am not saying my information is conclusive either by the way.

Its of no importance...anti histamines...which are the sedative ingredients in Calpol night are available everywhere

[Alice Purjorick]

I wonder why Miss Taken felt it necessary to educate us dummies on this particular detail?

The entertainment value of the responses ?

[Sunny]

Its of no importance...anti histamines...which are the sedative ingredients in Calpol night are available everywhere

the anti histamine is Diphenhydramine Hydrochloride and this is what is said about it.

CLINICAL PHARMACOLOGY:
Diphenhydramine hydrochloride is an antihistamine with anticholinergic (drying) and sedative effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.

A single oral dose of diphenhydramine hydrochloride is quickly absorbed with maximum activity occurring in approximately one hour. The duration of activity following an average dose of diphenhydramine hydrochloride is from four to six hours. Diphenhydramine is widely distributed throughout the body, including the CNS. Little, if any, is excreted unchanged in the urine; most appears as the degradation products of metabolic transformation in the liver, which are almost completely excreted within 24 hours.

here https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=75F0CDE5-C419-416D-9C13-BFC03BD83B1D

So there is a sedative affect- which you agree to.  I thought I'd confirm this.

[Sunny]

Davel thought Id ad that your anti histamine is the active ingredient in sleep aids too
https://www.huffingtonpost.co.uk/entry/zzzquil-ingredients_n_6902780

[Mr Gray]

the anti histamine is Diphenhydramine Hydrochloride and this is what is said about it.

CLINICAL PHARMACOLOGY:
Diphenhydramine hydrochloride is an antihistamine with anticholinergic (drying) and sedative effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.

A single oral dose of diphenhydramine hydrochloride is quickly absorbed with maximum activity occurring in approximately one hour. The duration of activity following an average dose of diphenhydramine hydrochloride is from four to six hours. Diphenhydramine is widely distributed throughout the body, including the CNS. Little, if any, is excreted unchanged in the urine; most appears as the degradation products of metabolic transformation in the liver, which are almost completely excreted within 24 hours.

here https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=75F0CDE5-C419-416D-9C13-BFC03BD83B1D

So there is a sedative affect- which you agree to.  I thought I'd confirm this.

I dont think its necessary to confirm anything which is an established fact

[Mr Gray]

Davel thought Id ad that your anti histamine is the active ingredient in sleep aids too
https://www.huffingtonpost.co.uk/entry/zzzquil-ingredients_n_6902780

its not my antihisatmine.........have you only just become aware calpol night contained an antihistamine

[Vertigo Swirl]

The entertainment value of the responses ?

that would tend to suggest trollish behaviour then.  Fancy suggesting such a thing!

[Sunny]

its not my antihisatmine.........have you only just become aware calpol night contained an antihistamine

Yes because I am new here and new to the case so just looked it up today.  I realise you have probably been around since the beginning but not all of us have your experience.

[Mr Gray]

Yes because I am new here and new to the case so just looked it up today.  I realise you have probably been around since the beginning but not all of us have your experience.

Its been discuused a lot and I doubt many will want to go through the same debate again

[Alice Purjorick]

that would tend to suggest trollish behaviour then.  Fancy suggesting such a thing!

Probably. Me being of Scandawegian ancestry Trolls are part of my heritage.
Oh but you have suggested it before; several times. "Sånt är livetas" they say in the better parts of
Skåne county

[Mr Gray]

Probably. Me being of Scandawegian ancestry Trolls are part of my heritage.
Oh but you have suggested it before; several times. "Sånt är livetas" they say in the better parts of
Skåne county

more like you have a very simple understanding of humour.....

[Mr Gray]

The entertainment value of the responses ?

these sort of goading posts that are allowed to stay is why posters with something interesting to say simply cannot be bothered to post

[Alice Purjorick]

more like you have a very simple understanding of humour.....

Oh indubitably old stick.

[Alice Purjorick]

these sort of goading posts that are allowed to stay is why posters with something interesting to say simply cannot be bothered to post

G-Unit jassi and MTI continue to post.