Not significantly.
I believe, however, the police will have an overall strategy for this sort of circumstance. Like: "we are going to give away nothing we do not want to".
The tactics for each interview will, in my opinion, be worked out on the hoof with the objective of reaching the end of the interview having not undermined the overall strategy. If the tactics used make them look daft to the uninformed layman I am sure they don't give the proverbial rat's wotsit provided the overall strategy has been preserved without compromise.
As for what the overall strategy is faites vos jeux.
edit: removed redundant word
That's not the impression I get from the strategy debrief in the Shannon case, nor from other documents / clips I've read / watched.
IMO, the aspects seem to be a) what and when to inform the media (on or off the record) about details related to the actual investigation; b) another seems to be broader in terms of public perception of the credibility of the police, and c) any impact on community relations.
We can all think of times when police forces (anywhere) have had egg-on-face situations for all sorts of reasons. I presume that a goal is to minimise them.
If that's the case, I can't think of a logical reason why the Met would have been so blunt early on that the McCanns and their friends were not suspects if they had not gone over everything that they had access to (including possibly informal interviews for any points that needed to be clarified subsequent to the review). IMO, it would have been much easier to stay waffly: all options open, egg-on-face avoidance.