The McCanns when asking the FLO if there was anything used to facilitate Madeleine’s abduction could merely have been fishing for information.
There were two related subjects mentioned to the FLO's. The crying the night before (it's still 'the twins', note, not Madeleine and Sean), and possible sedation.
The crying incident, they thought, may have been triggered by 'the abductor' the previous night.
As no-one cried on Thursday, perhaps 'the abductor' returned with the means of silencing the children?
Did the PJ find any evidence that Madeleine had been sedated?
I would like to mention that at approximately 20.00 on the 5th May, I arrived at the McCann apartment with other family communications officers. We were asked several times during this meeting about questions that Gerald and Kate would like to have followed up and responded to by the PJ.
I remember that during the meetings, Kate revealed that Madeleine had spoken with her in the morning of her disappearance and said that she remembered the twins had cried during the night and that she wanted to know why neither her mother or father had appeared. Kate asked herself whether this fact could have any relation with Madeleine’s disappearance.
Gerry and Kate also questioned whether there was any suggestion that pointed to the use of drugs to facilitate Madeleine's abduction.
http://www.mccannpjfiles.co.uk/PJ/JIM_McGARVEY.htm