Could all three children have been sedated by an intruder?

[Sunny]

A bit from Gerry's arguido statement


When questioned if the twins woke while the apartment was being searched, he replies negatively. When they were taken to another apartment he does not know if they woke as he did not take them. When asked, he says that this was not normal, and can find no reason for it happening. He still thought at this moment that the twins might have been drugged by the possible abductor, even if he only mentioned this to the Police several days later.

Why wait a few days later to tell the police this.

[Sunny]

Can you give me a cite where the patient will waken in an hour or so?

OK found it.

Intranasal: Analgesic effect: Up to 60 minutes (Carr 2004); Recovery: Children 2 to 6 years: 34 to 46 minutes (Bahetwar 2011)

https://www.drugs.com/ppa/ketamine.html

Can you find a cite for 8 hours now please.

[Mr Gray]

OK found it.

Intranasal: Analgesic effect: Up to 60 minutes (Carr 2004); Recovery: Children 2 to 6 years: 34 to 46 minutes (Bahetwar 2011)

https://www.drugs.com/ppa/ketamine.html

Can you find a cite for 8 hours now please.

That says analgesic effect..60 minutes
It doesn't say they wake up in 60 minutes

[G-Unit]

That says analgesic effect..60 minutes
It doesn't say they wake up in 60 minutes

A cite would be helpful.

[Mr Gray]

A cite would be helpful.

Sunny needs to provide the cite that children...wake up...after 60 mins....she's provided a cite re the analgesic effect so she obviously doesn't understand.

[Robittybob1]

I'll have a look at it.

[Sunny]

Sunny needs to provide the cite that children...wake up...after 60 mins....she's provided a cite re the analgesic effect so she obviously doesn't understand.

Here you are.

Following intravenous administration, ketamine produces anesthetic effect rapidly (within 30 seconds following a 2 milligram per kilogram dose) and lasts for about 5 to 10 minutes. Intramuscular administration produces anesthetic effects in 3 to 4 minutes, lasting 12 to 25 minutes. The sedative effects of ketamine can last for 45 minutes to 2.5 hours, which explains why sub-anesthetic doses can be used for analgesia alone. The larger the total dose of ketamine, the longer the time until complete recovery.

https://www.ems1.com/ems-products/narcotics-safes/articles/3031532-Ketamine-Drug-Whys/

Ok this time it is intravenous but I can't see the effect being longer than 2.5 hours if applied internasally.

Cite for 8 hours now Davel.  Show us YOU know what you are talking about, as you claim.

[Alice Purjorick]

Nope you obviously don't understand a word of what you are posting.

Not a convincing body swerve old top.
The question was related to time lapse NOT what is the correct term for according to.......?
So let's try to concentrate on that eh?
How about transposing it thus: "If the stuff is administered up someones 'ooter* for how long will it be effective"? your call at a time frame with whatever conditions you wish to put on it stated.
 
* apologies to any North American guests. Over here 'ooter is a nose 

[Sunny]

Nope you obviously don't understand a word of what you are posting.....it's intra nasally not inter nasally...but if you want to think you are the expert be my guest

I never claimed to know anything about it beyond googling. It was yourself that made that claim and yet again you have failed to provide the required cite. Do you have a reason for not responding to my request, perhaps you don't know what you are talking about.

[Mr Gray]

Not a convincing body swerve old top.
The question was related to time lapse NOT what is the correct term for according to.......?
So let's try to concentrate on that eh?
How about transposing it thus: "If the stuff is administered up someones 'ooter* for how long will it be effective"? your call at a time frame with whatever conditions you wish to put on it stated.
 
* apologies to any North American guests. Over here 'ooter is a nose 

Patient would be clinically sedated with analgesia for about an hour...with a half life of 2 to 3 hours...after 4 to 6 hours there would still be 25% of the original dose in the blood stream and after 6 to 9 hours 12.5%....not enough to provide clinical sedation or analgesia but enough to keep little Johnny in a nice deep sleep....sleep and 8 hrs being the points I replied to in gunits original post

[Sunny]

Patient would be clinically sedated with analgesia for about an hour...with a half life of 2 to 3 hours...after 4 to 6 hours there would still be 25% of the original dose in the blood stream and after 6 to 9 hours 12.5%....not enough to provide clinical sedation or analgesia but enough to keep little Johnny in a nice deep sleep....sleep and 8 hrs being the points I replied to in gunits original post

Cite that it would "keep little Johnny in a nice deep sleep....sleep and 8 hrs being the points I replied to in gunits original post" please. Only the third (or is it fourth) time of asking.

[Sunny]

I have provided a detailed explanation as to why a child would sleep for 8 hrs after a single dose of ketamine....I would think most posters understand it...the fact you don't is your problem

But no cite though Davel. Your detailed explanation as you call it is only your opinion without a correct cite.  Why should I or others believe you just because you say it. It isn't the first time you have failed to provide a cite when requested.

[G-Unit]

Patient would be clinically sedated with analgesia for about an hour...with a half life of 2 to 3 hours...after 4 to 6 hours there would still be 25% of the original dose in the blood stream and after 6 to 9 hours 12.5%....not enough to provide clinical sedation or analgesia but enough to keep little Johnny in a nice deep sleep....sleep and 8 hrs being the points I replied to in gunits original post

Does it have both alpha and beta half lives?

[faithlilly]

What evidence is there that the twins were not sedated. Not the drug test months later surely ? If we don’t know how they were sedated how do we know that they were tested for the correct drug ?

[ShiningInLuz]

What evidence is there that the twins were not?